CDAI Calculator

Calculate the Crohn's Disease Activity Index from eight clinical factors to summarize disease activity.

Crohn's Disease Activity Index
Use seven-day totals where requested and enter current clinical measurements.

About the CDAI

The Crohn's Disease Activity Index, usually abbreviated CDAI, is a research and clinical scoring system designed to summarize Crohn's disease activity. It combines symptoms recorded over seven days with examination findings and basic clinical measurements. The score was developed for trials and has become a familiar way to describe remission and degrees of active disease, but it does not replace a complete gastroenterology assessment. Eight weighted components contribute to the classic score. The seven-day number of liquid or very soft stools is multiplied by two. The sum of daily abdominal pain ratings is multiplied by five, and the sum of daily general well-being ratings is multiplied by seven. The number of recognized complications is multiplied by twenty. Use of an antidiarrheal such as diphenoxylate or an opioid for diarrhea adds thirty points. An abdominal mass contributes zero, twenty, or fifty points depending on whether it is absent, questionable, or definite. The hematocrit term compares the measured percentage with a reference of 47 for males or 42 for females, multiplying a positive deficit by six. The weight term expresses the shortfall between current and standard body weight as a percentage. This implementation does not subtract points when hematocrit exceeds the reference or current weight exceeds standard weight. The final weighted values are added and rounded to a whole-number CDAI score. Common interpretation bands define a score below 150 as clinical remission, 150 through 219 as mildly active disease, 220 through 449 as moderate to severe disease, and 450 or higher as severe or fulminant disease. Boundaries may be described slightly differently across protocols. A change of about 70 to 100 points has often been used to characterize a clinical response in research, but treatment decisions should not be based on a calculator alone. CDAI has important limitations. Several inputs are subjective, symptoms may arise from conditions other than active inflammation, and the score may not correlate closely with endoscopic healing. Modern care may also use biomarkers such as C-reactive protein or fecal calprotectin, imaging, endoscopy, patient-reported outcomes, nutrition, and complications. Ensure seven-day symptom totals are collected consistently and verify unusual results against the source data. This tool is intended for education and transparent score calculation. A clinician should interpret the result in context, particularly when symptoms worsen, weight falls, bleeding occurs, fever develops, or obstruction and abscess are possible. Severe pain, dehydration, persistent vomiting, fainting, or other urgent symptoms require prompt medical care.

CDAI examples

Clinical patternExample scoreActivity band
7 stools, pain 2, well-being 2, Hct 45, stable weight50Clinical remission in this male-reference example.
35 stools, pain 14, well-being 14, two complications, Hct 35, weight loss414Moderate to severe disease with antidiarrheal use and questionable mass.
14 stools, pain 7, well-being 7, one complication, Hct 40, stable weight162Mildly active disease using the male hematocrit reference.

How to calculate CDAI

  1. Total liquid stools, abdominal pain ratings, and general well-being ratings across seven days.
  2. Enter complications, medication use, abdominal mass category, and hematocrit reference sex.
  3. Enter current and standard body weight in the same unit.
  4. Select Calculate CDAI Score and review the score with its activity band.
  5. Discuss trends and supporting tests with the treating gastroenterology team.

CDAI FAQ

What does a CDAI score below 150 mean?

A score below 150 is conventionally categorized as clinical remission. Symptoms, biomarkers, and endoscopic inflammation may still require separate evaluation.

Are pain and well-being entered as averages?

No, the classic CDAI uses the sum of daily ratings over seven days. Using an average instead would substantially understate the calculated score.

Which complications count in CDAI?

The classic list includes arthritis or arthralgia, iritis or uveitis, erythema nodosum or related skin findings, anal disease, other fistula, and fever. Clinical definitions should follow the protocol being used.

Can CDAI show whether the bowel has healed?

No. CDAI emphasizes symptoms and does not directly measure mucosal inflammation or healing. Endoscopy, imaging, and biomarkers may provide complementary objective information.

Why does sex affect the score?

The original formula uses different hematocrit reference values for males and females. A deficit below the selected reference adds weighted points to the total.