Pediatric Epinephrine Dose Calculator

Calculate indication-specific pediatric epinephrine dose and volume for anaphylaxis, cardiac arrest, or severe croup.

Epinephrine dose estimate
Indication, route, and concentration are safety-critical. Use this educational calculation only within the appropriate emergency protocol.

About pediatric epinephrine dosing

Epinephrine is a time-critical medicine used in several pediatric emergencies, but the dose, route, concentration, and maximum depend on the indication. This calculator separates three common protocol calculations. For anaphylaxis, it estimates 0.01 mg/kg of the 1 mg/mL product by the intramuscular route, with a maximum of 0.5 mg. For cardiac arrest, it estimates 0.01 mg/kg by the intravenous or intraosseous route using the 0.1 mg/mL concentration, with a maximum of 1 mg. For severe croup, it estimates nebulized epinephrine at 0.5 mL/kg of the 1 mg/mL product, with a maximum volume of 5 mL. These regimens are not interchangeable. The 1 mg/mL and 0.1 mg/mL preparations differ by a factor of ten, and selecting the wrong concentration can cause a life-threatening error. The route is equally important: intramuscular epinephrine is the first-line route for anaphylaxis, while cardiac arrest dosing is given through IV or IO access under a resuscitation algorithm. Nebulized treatment for severe croup uses a different volume-based regimen and requires clinical observation because symptoms can recur. In suspected anaphylaxis, emergency treatment should not be delayed while using an online calculator. Activate emergency services, follow the applicable action plan, and use an available prescribed autoinjector when appropriate. Repeat dosing, airway management, fluids, oxygen, monitoring, and transport are determined by the response and local emergency guidance. In cardiac arrest, epinephrine is only one part of high-quality resuscitation, which prioritizes immediate CPR, rhythm assessment, defibrillation when indicated, and protocol timing. Severe croup with stridor at rest, respiratory fatigue, cyanosis, altered responsiveness, or poor air movement needs urgent professional care. The calculated number must be checked against the actual product label, patient weight, local guideline, age restrictions, maximum, and delivery device. Prefilled syringes and ampules may be labeled in ways that invite concentration confusion, so clinicians should communicate both milligrams and milliliters and perform an independent check whenever circumstances allow. This tool supports educational review and arithmetic verification; it does not diagnose an emergency, prescribe treatment, or replace trained judgment. If a child may need epinephrine now, seek emergency help and follow an established medical plan immediately.

Pediatric epinephrine examples

IndicationWeightCalculated example
Anaphylaxis, IM20 kg0.2 mg, or 0.2 mL of 1 mg/mL
Cardiac arrest, IV/IO15 kg0.15 mg, or 1.5 mL of 0.1 mg/mL
Severe croup, nebulized8 kg4 mg, or 4 mL of 1 mg/mL

How to use the calculator

  1. Confirm the child's measured weight in kilograms and identify the emergency indication.
  2. Select anaphylaxis, cardiac arrest, or severe croup to apply the matching route and concentration.
  3. Calculate the dose and read both the milligram and milliliter values.
  4. Independently verify the product concentration, maximum, route, and current emergency protocol before administration.

Frequently asked questions

What is the pediatric epinephrine dose for anaphylaxis?

A common emergency guideline is 0.01 mg/kg of the 1 mg/mL concentration intramuscularly, up to 0.5 mg. Follow the child's emergency plan and local guidance, and do not delay emergency care.

Why are two epinephrine concentrations shown?

Different indications and routes use products with different concentrations. The 1 mg/mL product is ten times as concentrated as 0.1 mg/mL, so confusing them is dangerous.

Is cardiac arrest dosing the same as anaphylaxis dosing?

No, although the milligram-per-kilogram number may look similar, the route, concentration, maximum, timing, and protocol differ. Cardiac arrest treatment must follow a complete pediatric resuscitation algorithm.

How is nebulized epinephrine calculated for croup?

This estimator uses 0.5 mL/kg of the 1 mg/mL product up to 5 mL. A child receiving nebulized epinephrine requires professional assessment and observation.

Should treatment wait for this calculation?

No, emergency response should never be delayed to use an online tool. Call emergency services and follow an established action plan or resuscitation protocol immediately.