EORTC Bladder Cancer Risk Calculator

Estimate recurrence and progression risk for non-muscle-invasive bladder cancer with EORTC risk tables.

EORTC recurrence and progression score
Select all six clinicopathological factors from the original EORTC model.

This historical risk model supports, but does not replace, specialist assessment. Treatment and surveillance should follow current guidelines and individual clinical factors.

About the EORTC bladder cancer risk tables

The EORTC risk tables estimate recurrence and progression after transurethral resection in patients with non-muscle-invasive bladder cancer. The model uses six features: number of tumors, largest tumor diameter, prior recurrence rate, pathologic T category, concurrent carcinoma in situ, and WHO 1973 tumor grade. Each feature contributes separate points to a recurrence score and a progression score. The total places the patient into a published risk band with probabilities at one and five years. Recurrence means a new bladder tumor after treatment, while progression means development of more advanced disease, typically muscle-invasive disease. Those outcomes are clinically different, so the scoring weights differ. For example, carcinoma in situ and T1 category contribute much more strongly to progression than to recurrence. The displayed percentages reproduce the commonly published EORTC table bands: recurrence totals range from 0 to 17 and progression totals range from 0 to 23. The original tables were developed from patients enrolled in European clinical trials. Many patients received intravesical chemotherapy, relatively few received modern maintenance bacillus Calmette-Guerin schedules, and grading used the 1973 WHO system. Contemporary practice, improved resection, repeat resection, enhanced cystoscopy, new pathology classification, and different intravesical treatments can change observed outcomes. The estimates may therefore overstate or understate risk for an individual treated today. Other models and current guideline risk groups may be more appropriate in particular settings. Use pathology and operative reports when selecting inputs. Tumor count refers to the number present at the evaluated recurrence, diameter refers to the largest lesion, and recurrence rate depends on documented tumor history. Carcinoma in situ should be selected only when confirmed. Grade must be mapped to the WHO 1973 G1, G2, or G3 categories; do not silently substitute a newer low-grade or high-grade label without pathology guidance. The result is intended for shared discussion with a urologist or oncology team. It cannot determine treatment by itself and does not include age, comorbidity, variant histology, lymphovascular invasion, prostatic urethral involvement, adequacy of resection, or response to prior therapy. Urgent symptoms and treatment decisions require direct clinical care.

EORTC scoring examples

Tumor profileScores and risksInterpretation
Single, under 3 cm, primary Ta G1, no CISRecurrence 0: 15.1% / 31.0%; progression 0: 0.2% / 0.8%Lowest table bands.
2 to 7, under 3 cm, recurrent Ta G2, no CISRecurrence 6: 38.0% / 62.0%; progression 5: 1.0% / 6.0%Intermediate published bands.
8 or more, 3 cm or greater, frequent T1 G3 with CISRecurrence 17: 61.0% / 78.0%; progression 23: 17.0% / 45.0%Highest table bands.

How to use this calculator

  1. Review the operative and pathology reports for all six factors.
  2. Select the tumor count, largest diameter, and recurrence history.
  3. Select T category, carcinoma in situ status, and WHO 1973 grade.
  4. Calculate and review recurrence and progression separately.
  5. Discuss the result alongside current guideline risk groups with a specialist.

Frequently asked questions

Who is this calculator for?

It was designed for non-muscle-invasive bladder cancer after transurethral resection. It is not a staging tool for muscle-invasive or metastatic cancer.

Are recurrence and progression the same?

No. Recurrence is a new bladder tumor, whereas progression is advancement to more serious disease. The EORTC model calculates separate scores because their predictors and consequences differ.

Which grading system should I use?

The original score uses WHO 1973 grades G1, G2, and G3. Ask the reporting pathologist or treating urologist how a newer pathology report should be mapped.

Why might modern outcomes differ?

The development cohorts predated several current diagnostic and treatment practices. Maintenance therapy, re-resection, improved imaging, and contemporary risk selection can affect observed risk.

Can the score choose my treatment?

No. Current guidelines, pathology details, prior treatment response, health status, and patient preferences all matter. A urologist should interpret the estimate and recommend surveillance or treatment.